5-Hydroxymebendazole（Cat No.:R013204）is a major active metabolite of mebendazole, a benzimidazole-class anthelmintic drug. It is formed through hepatic metabolism and contributes to the antiparasitic activity of the parent compound. Like mebendazole, 5-hydroxymebendazole disrupts microtubule polymerization by binding to β-tubulin, impairing glucose uptake and depleting energy stores in helminths, ultimately causing parasite death. Beyond its anthelmintic role, this metabolite has attracted interest in oncology research for its potential anticancer properties. Studies suggest it may inhibit tumor growth and angiogenesis, making it a promising candidate for drug repurposing investigations.