5-Fluoro-1-tetralone

• CAT Number: L023858
• CAS Number: 93742-85-9
• Molecular Formula: C10H9FO
• Molecular Weight: 164.18
• Purity: ≥95%
• IUPAC Name: 5-fluoro-3,4-dihydro-2H-naphthalen-1-one
• InChI: InChI=1S/C10H9FO/c11-9-5-1-4-8-7(9)3-2-6-10(8)12/h1,4-5H,2-3,6H2
• InChIKey: ALVLPJZOYNSRRX-UHFFFAOYSA-N
• SMILES: C1CC2=C(C=CC=C2F)C(=O)C1

5-Fluoro-1-tetralone(CAT: L023858) is a fluorinated aromatic ketone featuring a tetralone core substituted with a fluorine atom at the 5-position. This compound combines the reactivity of a cyclic ketone with the electronic effects of a strategically placed fluorine, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The fused benzocycloalkanone structure enables further functionalization through electrophilic substitution, nucleophilic additions, or enolate chemistry. 5-Fluoro-1-tetralone is commonly used in the development of CNS-active agents, kinase inhibitors, and fluorinated scaffolds in medicinal chemistry. Its structural rigidity and fluorine-enhanced metabolic stability contribute to improved pharmacokinetic profiles in drug discovery applications.