5-Chloro-2-thiophenecarboxylic Acid

• CAT Number: R012214
• CAS Number: 24065-33-6
• Molecular Formula: C5H3ClO2S
• Molecular Weight: 162.59
• Purity: ≥95%
• Synonyms: 2-Chloro-5-carboxythiophene; 5-Chlorothiophen-2-carboxylic acid; NSC 14776
• Storage: Store at -20°C
• IUPAC Name: 5-chlorothiophene-2-carboxylic acid
• InChI: InChI=1S/C5H3ClO2S/c6-4-2-1-3(9-4)5(7)8/h1-2H,(H,7,8)
• InChIKey: QZLSBOVWPHXCLT-UHFFFAOYSA-N
• SMILES: C1=C(SC(=C1)Cl)C(=O)O

5-Chloro-2-thiophenecarboxylic acid（Cat No.:R012214）is a halogenated heteroaromatic compound featuring a chlorine atom at the 5-position and a carboxylic acid group at the 2-position of the thiophene ring. This compound is widely used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and functional materials. The electron-rich thiophene ring and electron-withdrawing substituents make it reactive in cross-coupling, acylation, and esterification reactions. It is typically supplied as a crystalline solid, soluble in polar organic solvents, and valued for its utility in constructing sulfur-containing heterocyclic frameworks with tailored electronic properties.