5-Chloro-2-Thiophenecarbonyl Chloride

• CAT Number: R030296
• CAS Number: 42518-98-9
• Molecular Formula: C5H2Cl2OS
• Molecular Weight: 181.03
• Purity: ≥95%
• Synonyms: 5-Chloro-2-thenoyl Chloride; 5-Chloro-2-thienoyl Chloride; 5-Chloro-2-thienylcarbonyl Chloride; 5-Chloro-2-thiophenecarbonyl Chloride;?5-Chlorothiophen-2-carboxylic Acid Chloride?
• Storage: -20°C
• IUPAC Name: 5-chlorothiophene-2-carbonyl chloride
• InChI: InChI=1S/C5H2Cl2OS/c6-4-2-1-3(9-4)5(7)8/h1-2H
• InChIKey: BMPDCQVRKDNUAP-UHFFFAOYSA-N
• SMILES: C1=C(SC(=C1)Cl)C(=O)Cl

5-Chloro-2-thiophenecarbonyl chloride (Cat No.: R030296) is a reactive heterocyclic acyl chloride derived from thiophene, featuring a chlorine atom at the 5-position and a carbonyl chloride group at the 2-position. It is commonly used as a building block in organic synthesis, particularly for preparing thiophene-based derivatives, pharmaceuticals, and agrochemicals. The acyl chloride functionality enables facile coupling with amines, alcohols, or thiols to form amides, esters, or thioesters. Its electron-rich thiophene ring contributes to bioactivity and functional versatility in medicinal chemistry applications.