5-Chloro-2-pyridinamine

• CAT Number: R043229
• CAS Number: 1072-98-6
• Molecular Formula: C5H5ClN2
• Molecular Weight: 128.56
• Purity: ≥95%
• Synonyms: 2-Amino-5-chloro-pyridine; (5-Chloropyridin-2-yl)amine; 2-Amino-5-chloropyridine; 5-Chloro-2-aminopyridine; 5-Chloro-2-pyridinamine; 5-Chloro-2-pyridineamine; 5-Chloro-α-aminopyridine; NSC 26283; RP 26695
• Storage: -20°C
• IUPAC Name: 5-chloropyridin-2-amine
• InChI: InChI=1S/C5H5ClN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
• InChIKey: MAXBVGJEFDMHNV-UHFFFAOYSA-N
• SMILES: C1=CC(=NC=C1Cl)N

5-Chloro-2-pyridinamine(CAT: R043229) is a halogenated aminopyridine compound featuring a chlorine atom at the 5-position and an amino group at the 2-position of the pyridine ring. This heterocyclic building block is valuable in medicinal chemistry, agrochemical synthesis, and heterocycle modification, offering versatile reactivity for further functionalization via nucleophilic aromatic substitution, cross-coupling reactions, or amide bond formation. Its electron-rich amino group and electron-withdrawing chloro substituent create useful electronic asymmetry on the aromatic ring, facilitating selective transformations. Commonly employed in the synthesis of biologically active molecules and pharmaceutical intermediates.