5-Chloro-1-methyl-4-nitroimidazole

• CAT Number: R006600
• CAS Number: 4897-25-0
• Molecular Formula: C4H4ClN3O2
• Molecular Weight: 161.55
• Purity: ≥95%
• Synonyms: 5-Chloro-1-methyl-4-nitro-1H-imidazole; 1-Methyl-4-nitro-5-chloroimidazole; NSC 7852
• Storage: -20°C
• IUPAC Name: 5-chloro-1-methyl-4-nitroimidazole
• InChI: InChI=1S/C4H4ClN3O2/c1-7-2-6-4(3(7)5)8(9)10/h2H,1H3
• InChIKey: OSJUNMSWBBOTQU-UHFFFAOYSA-N
• SMILES: CN1C=NC(=C1Cl)[N+](=O)[O-]

5-Chloro-1-methyl-4-nitroimidazole (Cat No.: R006600) is a halogenated nitroimidazole derivative commonly used as an intermediate in the synthesis of antimicrobial and antiprotozoal agents, such as metronidazole analogs. Its structure includes a nitro group at the 4-position, a chlorine atom at the 5-position, and a methyl group on the nitrogen at position 1, contributing to its reactivity and biological relevance. The compound is particularly valuable in medicinal chemistry for developing drugs targeting anaerobic bacteria and protozoa by disrupting DNA synthesis and function.