5-Bromopyrimidine-2-carboxylic Acid Methyl Ester

• CAT Number: R024211
• CAS Number: 89581-38-4
• Molecular Formula: C6H5BrN2O2
• Molecular Weight: 217.02
• Purity: ≥95%
• Synonyms: Methyl 5-Bromopyrimidine-2-carboxylate
• Storage: Store at -20°C
• IUPAC Name: methyl 5-bromopyrimidine-2-carboxylate
• InChI: InChI=1S/C6H5BrN2O2/c1-11-6(10)5-8-2-4(7)3-9-5/h2-3H,1H3
• InChIKey: XILAKTMDKMVJQV-UHFFFAOYSA-N
• SMILES: COC(=O)C1=NC=C(C=N1)Br

5-Bromopyrimidine-2-carboxylic Acid Methyl Ester（Cat No.:R024211）is a halogenated pyrimidine derivative featuring a bromine atom at the 5-position and a methyl ester group at the 2-position of the heterocyclic ring. It serves as a key intermediate in the synthesis of pharmaceutical compounds, agrochemicals, and heterocyclic libraries. The bromine substituent allows for versatile functionalization through cross-coupling reactions such as Suzuki or Buchwald–Hartwig. Meanwhile, the ester group enables further modifications via hydrolysis or amidation. Its dual reactivity makes it ideal for building complex, bioactive scaffolds in medicinal chemistry.