5-Bromo-2,4-dimethoxypyrimidine

• CAT Number: R001194
• CAS Number: 56686-16-9
• Molecular Formula: C6H7BrN2O2
• Molecular Weight: 219.04
• Purity: ≥95%
• Synonyms: 2,4-Dimethoxy-5-bromopyrimidine; 5-Bromo-2,4-bis(methyloxy)pyrimidine; NSC 81442
• Storage: Store at -20°C
• IUPAC Name: 5-bromo-2,4-dimethoxypyrimidine
• InChI: InChI=1S/C6H7BrN2O2/c1-10-5-4(7)3-8-6(9-5)11-2/h3H,1-2H3
• InChIKey: QEZIMQMMEGPYTR-UHFFFAOYSA-N
• SMILES: COC1=NC(=NC=C1Br)OC

5-Bromo-2,4-dimethoxypyrimidine (Cat No.: R001194) is a substituted pyrimidine compound featuring bromine at the 5-position and methoxy groups at the 2- and 4-positions of the pyrimidine ring. It serves as a versatile intermediate in the synthesis of pharmaceuticals, agrochemicals, and heterocyclic compounds. The bromine atom allows for further functionalization via cross-coupling reactions such as Suzuki or Buchwald–Hartwig coupling. Its electron-rich methoxy groups enhance reactivity, making it valuable in medicinal chemistry for developing pyrimidine-based bioactive molecules and structure–activity relationship (SAR) studies.