5-Bromo-2-chloro-3-fluoropyridine

• CAT Number: L037799
• CAS Number: 831203-13-5
• Molecular Formula: C5H2BrClFN
• Molecular Weight: 210.43
• Purity: ≥95%
• IUPAC Name: 5-bromo-2-chloro-3-fluoropyridine
• InChI: InChI=1S/C5H2BrClFN/c6-3-1-4(8)5(7)9-2-3/h1-2H
• InChIKey: OEKXUEWGXWCENG-UHFFFAOYSA-N
• SMILES: C1=C(C=NC(=C1F)Cl)Br

5-Bromo-2-chloro-3-fluoropyridine(CAT: L037799) is a halogenated pyridine derivative featuring bromine, chlorine, and fluorine atoms strategically positioned on the aromatic ring. This compound serves as a valuable intermediate in pharmaceutical, agrochemical, and materials chemistry due to its electron-deficient pyridine core and multiple reactive halogen sites. It is particularly suited for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald–Hartwig, and Stille), allowing for the construction of diverse functionalized heterocycles. The presence of three different halogens enables regioselective transformations and fine-tuning of electronic properties. It is widely used in the synthesis of kinase inhibitors, fluorinated ligands, and heterocyclic scaffolds for drug discovery and development.