5-Bromo-2-aminopyrimidine

• CAT Number: R004063
• CAS Number: 7752-82-1
• Molecular Formula: C4H4BrN3
• Molecular Weight: 174.00
• Purity: ≥95%
• Synonyms: 5-Bromo-2-pyrimidinamine; 2-Amino-5-bromo-pyrimidine; 2-Amino-5-bromopyrimidine; 5-Bromo-2-pyrimidinamine; 5-Bromopyrimidin-2-ylamine; NSC 27269
• Storage: Store at -20°C
• IUPAC Name: 5-bromopyrimidin-2-amine
• InChI: InChI=1S/C4H4BrN3/c5-3-1-7-4(6)8-2-3/h1-2H,(H2,6,7,8)
• InChIKey: UHRHPPKWXSNZLR-UHFFFAOYSA-N
• SMILES: C1=C(C=NC(=N1)N)Br

5-Bromo-2-aminopyrimidine（Cat No.:R004063）is a halogenated heterocyclic compound featuring a bromine atom at the 5-position and an amino group at the 2-position of the pyrimidine ring. It serves as a versatile intermediate in the synthesis of pharmaceuticals, agrochemicals, and biologically active molecules. The bromine atom allows for selective functionalization via cross-coupling reactions such as Suzuki or Buchwald–Hartwig amination, while the amino group enables further derivatization. This compound is commonly used in medicinal chemistry for designing kinase inhibitors and nucleoside analogs. It is typically supplied as a crystalline solid, soluble in polar organic solvents.