5-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine

• CAT Number: L028438
• CAS Number: 858116-66-2
• Molecular Formula: C16H25BrN2Si
• Molecular Weight: 353.37
• Purity: ≥95%
• IUPAC Name: (5-bromopyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane
• InChI: InChI=1S/C16H25BrN2Si/c1-11(2)20(12(3)4,13(5)6)19-8-7-14-9-15(17)10-18-16(14)19/h7-13H,1-6H3
• InChIKey: UJUSITKTVXDVLQ-UHFFFAOYSA-N
• SMILES: CC(C)[Si](C(C)C)(C(C)C)N1C=CC2=CC(=CN=C21)Br

5-Bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine（Cat No.:L028438）is a heteroaromatic compound featuring a pyrrolo[2,3-b]pyridine core, a bromine atom at the 5-position, and a triisopropylsilyl (TIPS) protecting group on the nitrogen at the 1-position. The TIPS group provides steric protection and enhances compound stability during multi-step synthesis, while the bromine substituent enables palladium-catalyzed cross-coupling reactions such as Suzuki, Sonogashira, or Buchwald–Hartwig. This compound is widely used as a synthetic intermediate in medicinal chemistry and materials science, particularly for the construction of complex heterocyclic systems and development of bioactive molecules or electronic materials.