5-Aminosalicylic Acid-d3 hydrochloride

• CAT Number: R072175
• CAS Number: 1346601-18-0
• Molecular Formula: C7H5D3ClNO3
• Molecular Weight: 192.61
• Purity: ≥95%
• Synonyms: 3-amino-2,4,5-trideuterio-6-hydroxybenzoic acid;hydrochloride
• InChI: InChI=1S/C7H7NO3.ClH/c8-4-1-2-6(9)5(3-4)7(10)11;/h1-3,9H,8H2,(H,10,11);1H/i1D,2D,3D
• InChIKey: KKRSNTURHSOKTM-KADUPEOVSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1N)[2H])C(=O)O)O)[2H].Cl

5-Aminosalicylic Acid-d₃ hydrochloride（Cat No.:R072175）is a deuterium-labeled form of 5-aminosalicylic acid (mesalamine), an anti-inflammatory agent widely used in the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease. The incorporation of three deuterium atoms allows for precise quantification and metabolic tracking using mass spectrometry. The hydrochloride salt enhances solubility and stability for analytical applications. While biologically similar to the non-labeled form, 5-Aminosalicylic Acid-d₃ hydrochloride is primarily used as an internal standard in pharmacokinetic and drug metabolism studies to ensure accurate assessment of mesalamine levels in biological matrices.