For research use only. Not for therapeutic Use.
4BP-TQS（Cat No.:I010922）is a positive allosteric modulator and agonist of the α7 nicotinic acetylcholine receptor (α7 nAChR), a ligand-gated ion channel involved in cognitive function, neuroprotection, and inflammation. By enhancing receptor sensitivity and function, 4BP-TQS promotes calcium influx and neurotransmitter release, supporting synaptic plasticity and neuronal signaling. It is widely used in neuroscience research to study cholinergic modulation, learning, memory, and neuroinflammatory conditions such as Alzheimer’s disease and schizophrenia. 4BP-TQS is a valuable tool for exploring α7 nAChR-targeted therapies and advancing drug discovery in cognitive and neurodegenerative disorders.
| CAS Number | 360791-49-7 |
| Synonyms | 4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide |
| Molecular Formula | C18H17BrN2O2S |
| Purity | ≥95% |
| IUPAC Name | 4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide |
| InChI | InChI=1S/C18H17BrN2O2S/c19-12-6-4-11(5-7-12)18-15-3-1-2-14(15)16-10-13(24(20,22)23)8-9-17(16)21-18/h1-2,4-10,14-15,18,21H,3H2,(H2,20,22,23) |
| InChIKey | YNCXHXYZTLIZTO-UHFFFAOYSA-N |
| SMILES | C1C=CC2C1C(NC3=C2C=C(C=C3)S(=O)(=O)N)C4=CC=C(C=C4)Br |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
