4,4/'-Diphenylmethane diisocyanate

• CAT Number: M069572
• CAS Number: 101-68-8
• Molecular Formula: C15H10N2O2
• Molecular Weight: 250.26
• Purity: ≥95%
• Synonyms: Diphenylmethane diisocyanate; Bis(4-isocyanatophenyl)methane; Isonate
• Storage: -20°C
• IUPAC Name: 1-isocyanato-4-[(4-isocyanatophenyl)methyl]benzene
• InChI: InChI=1S/C15H10N2O2/c18-10-16-14-5-1-12(2-6-14)9-13-3-7-15(8-4-13)17-11-19/h1-8H,9H2
• InChIKey: UPMLOUAZCHDJJD-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1CC2=CC=C(C=C2)N=C=O)N=C=O

4,4′-Diphenylmethane diisocyanate (Cat No.: M069572) is an aromatic diisocyanate composed of two isocyanate groups attached to a diphenylmethane backbone. This solid, off-white to pale yellow compound is a key raw material in the production of polyurethane foams, elastomers, adhesives, and coatings. MDI reacts readily with polyols to form rigid and flexible polyurethanes used in insulation, automotive parts, and furniture. Its favorable balance of reactivity, mechanical properties, and cost-efficiency makes it one of the most widely used industrial isocyanates.

Reference

1.Herrick, Christina A., et al. "A novel mouse model of diisocyanate-induced asthma showing allergic-type inflammation in the lung after inhaled antigen challenge." Journal of allergy and clinical immunology 109.5 (2002): 873-878.
2.Lushniak, Boris D., et al. "Indirect assessment of 4, 4′‐diphenylmethane diisocyanate (MDI) exposure by evaluation of specific humoral immune responses to MDI conjugated to human serum albumin." American journal of industrial medicine 33.5 (1998): 471-477.