For research use only. Not for therapeutic Use.
4-(Trifluoromethyl)aniline（Cat No.:R011837）is an aromatic amine with the molecular formula C7H6F3N. It features a trifluoromethyl group (-CF3) attached to the benzene ring at the para position relative to the amino group (-NH2). This compound appears as a colorless to light yellow solid and is widely used in organic synthesis, particularly for the production of pharmaceuticals, agrochemicals, and other fine chemicals. The electron-withdrawing trifluoromethyl group enhances the compound’s reactivity and can influence the biological activity of derivatives. It is also studied for its potential role in modifying drug potency and selectivity.
| CAS Number | 455-14-1 |
| Synonyms | USP Leflunomide Related Compound A; 4-(Trifluoromethyl)benzenamine; 4-Amino-α,α,α-benzotrifluoride; 4-Aminobenzotrifluoride; NSC 10337; p-(Trifluoromethyl)aniline; p-Amino-α,α,α-trifluorotoluene; p-Aminobenzotrifluoride; p-Trifluoromethylphenylamine; |
| Molecular Formula | C7H6F3N |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 4-(trifluoromethyl)aniline |
| InChI | InChI=1S/C7H6F3N/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4H,11H2 |
| InChIKey | ODGIMMLDVSWADK-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C(F)(F)F)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
