4-Tolylsulfonamide

• CAT Number: R017437
• CAS Number: 70-55-3
• Molecular Formula: C7H9NO2S
• Molecular Weight: 171.21
• Purity: ≥95%
• Synonyms: 4-Methylbenzenesulfonamide; p-Toluenesulfonamide; 4-Methylbenzene-1-sulfonamide; 4-Methylbenzenesulfonamide; 4-Methylbenzensulfonamide; 4-Methylphenylsulfonamide; 4-Tolylsulfonamide; NSC 9908; Plasticizer 15; Toluene-4-sulfonamide; Tolylsulfonamide
• Storage: -20°C
• IUPAC Name: 4-methylbenzenesulfonamide
• InChI: InChI=1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)
• InChIKey: LMYRWZFENFIFIT-UHFFFAOYSA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)N

4-Tolylsulfonamide（Cat No.:R017437）is an aromatic sulfonamide compound featuring a tolyl group (a methyl-substituted phenyl ring) at the para (4-) position relative to the sulfonamide (-SO₂NH₂) group. It appears as a white to off-white crystalline solid and is moderately soluble in organic solvents. 4-Tolylsulfonamide serves as a key intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of sulfa drugs, enzyme inhibitors, and functionalized heterocycles. Its sulfonamide group enables hydrogen bonding and electrophilic substitution, making it valuable in medicinal chemistry, structure–activity relationship (SAR) studies, and the design of bioactive molecules.