4-tert-Butylacetophenone

• CAT Number: R049398
• CAS Number: 943-27-1
• Molecular Formula: C12H16O
• Molecular Weight: 176.26
• Purity: ≥95%
• Synonyms: 1-[4-(1,1-Dimethylethyl)phenyl]ethanone; 1-(4-tert-Butylphenyl)ethanone; 4-tert-Butylphenyl Methyl Ketone; NSC 826
• Storage: Store at -20C
• IUPAC Name: 1-(4-tert-butylphenyl)ethanone
• InChI: InChI=1S/C12H16O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-8H,1-4H3
• InChIKey: UYFJYGWNYQCHOB-UHFFFAOYSA-N
• SMILES: CC(=O)C1=CC=C(C=C1)C(C)(C)C

4-tert-Butylacetophenone（Cat No.:R049398）is an aromatic ketone composed of an acetophenone core with a bulky tert-butyl group at the para (4-) position. This compound is widely used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. The tert-butyl group imparts steric hindrance and lipophilicity, influencing the reactivity and solubility of derivatives. Its electron-donating effect can affect the electronic distribution across the aromatic ring, making it valuable in electrophilic substitution reactions. It also serves as a precursor for ligands, polymers, and fragrance components.