(4-(N,N-Dimethylamino)phenyl)di-tert-butyl phosphine

• CAT Number: L034949
• CAS Number: 932710-63-9
• Molecular Formula: C16H28NP
• Molecular Weight: 265.37
• Purity: ≥95%
• IUPAC Name: 4-ditert-butylphosphanyl-N,N-dimethylaniline
• InChI: InChI=1S/C16H28NP/c1-15(2,3)18(16(4,5)6)14-11-9-13(10-12-14)17(7)8/h9-12H,1-8H3
• InChIKey: IQTHEAQKKVAXGV-UHFFFAOYSA-N
• SMILES: CC(C)(C)P(C1=CC=C(C=C1)N(C)C)C(C)(C)C

(4-(N,N-Dimethylamino)phenyl)di-tert-butylphosphine（Cat No.:L034949）is an electron-rich, sterically hindered phosphine ligand featuring a dimethylamino-substituted phenyl ring and two bulky tert-butyl groups attached to the phosphorus atom. This compound is widely used in homogeneous catalysis, particularly in palladium- and nickel-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig amination. The electron-donating dimethylamino group enhances the ligand’s basicity and coordination strength, while the bulky tert-butyl groups promote selectivity and reduce unwanted side reactions. It is especially valuable in challenging catalytic transformations requiring highly active, tunable ligands with strong σ-donor and steric properties.