4-(N-tert-Butoxycarbonyl)aminobenzoic Acid

• CAT Number: R018401
• CAS Number: 66493-39-8
• Molecular Formula: C12H15NO4
• Molecular Weight: 237.26
• Purity: ≥95%
• Synonyms: 4-(tert-Butoxycarbonylamino)benzoic Acid; p-(tert-Butoxycarbonylamino)benzoic Acid; (4-Carboxyphenyl)carbamic Acid tert-Butyl Ester; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]benzoic Acid
• Storage: -20°C
• IUPAC Name: 4-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic acid
• InChI: InChI=1S/C12H15NO4/c1-12(2,3)17-11(16)13-9-6-4-8(5-7-9)10(14)15/h4-7H,1-3H3,(H,13,16)(H,14,15)
• InChIKey: ZJDBQMWMDZEONW-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NC1=CC=C(C=C1)C(=O)O

4-(N-tert-Butoxycarbonyl)aminobenzoic acid（Cat No.:R018401）is a protected aromatic amino acid derivative, featuring a para-substituted amino group shielded by a tert-butoxycarbonyl (Boc) protecting group and a carboxylic acid on the benzene ring. This white to off-white solid is commonly used in peptide synthesis and medicinal chemistry, where the Boc group protects the amine during selective reactions. Its stability under mildly acidic conditions allows for orthogonal deprotection strategies. The compound serves as a versatile intermediate in the design of drug candidates, fluorescent probes, and functionalized polymers for biomedical and material science applications.