4-Morpholineethanesulfonic Acid Hydrate

• CAT Number: R031104
• CAS Number: 145224-94-8
• Molecular Formula: C6H15NO5S
• Molecular Weight: 213.25
• Purity: ≥95%
• Synonyms: 2-(4-Morpholino)ethanesulfonic Acid Hydrate; 2-(4-Morpholinyl)ethanesulfonic Acid Hydrate; 2-(N-Morpholino)ethanesulfonic Acid Hydrate; 2-Morpholinoethanesulfonic Acid Hydrate; MES Hydrate; MES Hydrate (buffering agent); Morpholinoethanesulfonic Acid
• Storage: -20°C
• IUPAC Name: 2-morpholin-4-ylethanesulfonic acid;hydrate
• InChI: InChI=1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2
• InChIKey: MIIIXQJBDGSIKL-UHFFFAOYSA-N
• SMILES: C1COCCN1CCS(=O)(=O)O.O

4-Morpholineethanesulfonic acid hydrate (CAT: R031104) is a zwitterionic buffering agent widely used in biological and biochemical research. Derived from morpholine, MES contains both a sulfonic acid group and a secondary amine, giving it excellent buffering capacity in the pH range of 5.5 to 6.7, ideal for maintaining physiological conditions in cell culture, protein purification, and enzyme assays. The hydrate form improves solubility and handling. MES is water-soluble, chemically stable, and shows minimal interference with biochemical reactions, UV absorbance, or metal ions.