4-(Methylnitrosamino-d3)-1-(3-pyridyl)-1-butanol N-β-D-Glucuronide

• CAT Number: R004390
• CAS Number: NA
• Molecular Formula: C₁₆H₂₀D₃N₃O₈
• Molecular Weight: 388.39
• Purity: ≥95%
• Synonyms: 1-β-D-Glucopyranuronosyl-3-[(1RS)-1-hydroxy-4-(methyl-d3-nitrosoamino)butyl]pyridinium Inner Salt; NNAL-d3-N-β-D-glucuronide
• Storage: 2°C to 8°C

4-(Methylnitrosamino-d3)-1-(3-pyridyl)-1-butanol N-β-D-Glucuronide（Cat No.:R004390） is a deuterated metabolite of nicotine-derived nitrosamine ketone, where three hydrogen atoms are replaced with deuterium. This compound is crucial for studying the metabolic and carcinogenic pathways of tobacco-related nitrosamines in humans. The addition of the glucuronide group enhances solubility and excretion, facilitating its detection in biological fluids such as urine. This modification is key in epidemiological studies to assess exposure to harmful tobacco compounds, aiding in understanding the risk factors for tobacco-related cancers and developing strategies for prevention and reduction.