4-Methyl-2-oxopentanoic acid

• CAT Number: I019912
• CAS Number: 816-66-0
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 130.14
• Purity: ≥95%
• Target: Endogenous Metabolite
• IUPAC Name: 4-methyl-2-oxopentanoic acid
• InChI: InChI=1S/C6H10O3/c1-4(2)3-5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9)
• InChIKey: BKAJNAXTPSGJCU-UHFFFAOYSA-N
• SMILES: CC(C)CC(=O)C(=O)O

4-Methyl-2-oxopentanoic acid（Cat No.:I019912）, also known as α-ketoisocaproic acid (KIC), is a keto acid with the molecular formula C6H10O3. It is an intermediate in the catabolism of the branched-chain amino acid leucine. KIC is formed by the transamination of leucine and can be further metabolized into isovaleryl-CoA or converted into other energy-yielding compounds. It plays a role in energy production and nitrogen metabolism, particularly in muscle tissue. KIC is used in metabolic and nutritional research and may be supplemented in clinical settings for individuals with disorders of amino acid metabolism.