4-(Methoxycarbonyl)bicyclo[2.2.2]octane-1-carboxylic Acid

• CAT Number: R023030
• CAS Number: 18720-35-9
• Molecular Formula: C11H16O4
• Molecular Weight: 212.24
• Purity: ≥95%
• Synonyms: Bicyclo[2.2.2]octane-1,4-dicarboxylic Acid Monomethyl Ester
• Storage: Store at RT
• IUPAC Name: 4-methoxycarbonylbicyclo[2.2.2]octane-1-carboxylic acid
• InChI: InChI=1S/C11H16O4/c1-15-9(14)11-5-2-10(3-6-11,4-7-11)8(12)13/h2-7H2,1H3,(H,12,13)
• InChIKey: KBZVAQVEHVGIEI-UHFFFAOYSA-N
• SMILES: COC(=O)C12CCC(CC1)(CC2)C(=O)O

4-(Methoxycarbonyl)bicyclo[2.2.2]octane-1-carboxylic Acid(CAT: R023030) is a rigid bicyclic carboxylic acid derivative featuring both a carboxyl and a methoxycarbonyl functional group. Its sterically constrained bicyclo[2.2.2]octane core imparts unique conformational properties, making it a valuable scaffold in medicinal chemistry and synthetic design. Researchers employ this compound as a building block for peptidomimetics, bioisosteres, and conformationally restricted ligands, aiding in drug discovery programs targeting improved binding affinity and metabolic stability. Beyond pharmaceuticals, it is explored in materials and polymer chemistry, where rigid bicyclic units can influence molecular packing and mechanical strength. Its dual functionality enhances versatility across synthetic and biomedical applications.