4-Formylpiperidine-1-carboxylic Acid tert-Butyl Ester

• CAT Number: R012888
• CAS Number: 137076-22-3
• Molecular Formula: C11H19NO3
• Molecular Weight: 213.28
• Purity: ≥95%
• Synonyms: 4-Formyl-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl 4-Formyl-1-piperidinecarboxylate; 1-(tert-Butoxycarbonyl)-4-formylpiperidine; 1-Boc-4-formylpiperidine; 1-Boc-4-piperidinecarboxaldehyde
• Storage: -20°C
• IUPAC Name: tert-butyl 4-formylpiperidine-1-carboxylate
• InChI: InChI=1S/C11H19NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h8-9H,4-7H2,1-3H3
• InChIKey: JYUQEWCJWDGCRX-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC(CC1)C=O

4-Formylpiperidine-1-carboxylic acid tert-butyl ester (Cat No.: R012888) is a synthetic intermediate featuring a piperidine ring substituted with a formyl group at the 4-position and a tert-butyl ester-protected carboxylic acid on the nitrogen. The formyl group provides a reactive aldehyde functionality for further derivatization, such as reductive amination or condensation reactions. The tert-butyl ester protects the carboxyl group during multistep synthesis, allowing selective transformations. This compound is widely used in medicinal chemistry for constructing complex heterocyclic structures and drug-like molecules.