(4-Fluoro-3,5-dimethylphenyl)boronic acid

• CAT Number: L002511
• CAS Number: 342636-66-2
• Molecular Formula: C8H10BFO2
• Molecular Weight: 167.98
• Purity: ≥95%
• IUPAC Name: (4-fluoro-3,5-dimethylphenyl)boronic acid
• InChI: InChI=1S/C8H10BFO2/c1-5-3-7(9(11)12)4-6(2)8(5)10/h3-4,11-12H,1-2H3
• InChIKey: PQIOZTCJOZUCMI-UHFFFAOYSA-N
• SMILES: B(C1=CC(=C(C(=C1)C)F)C)(O)O

(4-Fluoro-3,5-dimethylphenyl)boronic acid(CAT: L002511) is an organoboron compound widely used as a coupling partner in Suzuki–Miyaura cross-coupling reactions. Featuring a fluorinated and methylated aromatic ring, it offers enhanced electronic tuning for the construction of substituted biaryl systems. This boronic acid is a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and functional materials, enabling precise modification of molecular frameworks. The fluorine atom contributes to metabolic stability and altered binding affinity in drug design, while the methyl groups influence steric and electronic properties. Its high reactivity, stability, and compatibility with palladium catalysts make it ideal for modern organic synthesis applications.