4-Fluoro-3-chloroaniline

• CAT Number: R021749
• CAS Number: 367-21-5
• Molecular Formula: C6H5ClFN
• Molecular Weight: 145.56
• Purity: ≥95%
• Synonyms: 3-Chloro-4-fluorobenzenamine; 3-Chloro-4-fluoroaniline; 3-Chloro-4-fluorobenzenamine; 3-Chloro-4-fluorophenylamine; NSC 10290; m-Chloro-p-fluoroaniline
• Storage: -20°C
• IUPAC Name: 3-chloro-4-fluoroaniline
• InChI: InChI=1S/C6H5ClFN/c7-5-3-4(9)1-2-6(5)8/h1-3H,9H2
• InChIKey: YSEMCVGMNUUNRK-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C=C1N)Cl)F

4-Fluoro-3-chloroaniline(CAT: R021749) is a halogenated aromatic amine with the molecular formula C₆H₅ClFN. It features both fluorine and chlorine substituents on the benzene ring, positioned ortho and meta to the amino group, respectively. This dual halogenation modulates the compound’s electronic properties, making it a versatile intermediate in organic synthesis. It is widely used in the production of pharmaceuticals, agrochemicals, and dyes, where the halogen atoms serve as handles for cross-coupling and other substitution reactions. Its reactivity profile supports the development of heterocycles, aromatic derivatives, and bioactive molecules in medicinal chemistry and fine chemical manufacturing.