4-DAMP

• CAT Number: R016860
• CAS Number: 1952-15-4
• Molecular Formula: C21H26INO2
• Molecular Weight: 451.34
• Purity: ≥95%
• Synonyms: (1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetate;iodide
• InChI: InChI=1S/C21H26NO2.HI/c1-22(2)15-13-19(14-16-22)24-21(23)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;/h3-12,19-20H,13-16H2,1-2H3;1H/q+1;/p-1
• InChIKey: WWJHRSCUAQPFQO-UHFFFAOYSA-M
• SMILES: C[N+]1(CCC(CC1)OC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3)C.[I-]

4-DAMP (Cat No.:R016860) is a potent, selective antagonist of muscarinic acetylcholine M3 receptors, widely used in pharmacological research to study cholinergic signaling. By inhibiting M3 receptor activity, 4-DAMP helps elucidate the role of muscarinic pathways in smooth muscle contraction, glandular secretion, and various autonomic functions. It is especially valuable in exploring therapeutic approaches for respiratory, gastrointestinal, and urinary disorders involving overactive muscarinic signaling. Due to its high affinity and selectivity, 4-DAMP is an essential tool for dissecting M3-mediated physiological responses and developing receptor-specific treatments.