4-CMTB

• CAT Number: I010996
• CAS Number: 300851-67-6
• Molecular Formula: C14H15ClN2OS
• Molecular Weight: 294.80
• Purity: ≥95%
• Synonyms: 2-(4-chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide
• InChI: InChI=1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)
• InChIKey: AZYDQCGCBQYFSE-UHFFFAOYSA-N
• SMILES: CC(C)C(C1=CC=C(C=C1)Cl)C(=O)NC2=NC=CS2

4-CMTB（Cat No.:I010996）is a selective small-molecule agonist of the formyl peptide receptor 2 (FPR2/ALX), a G-protein–coupled receptor involved in inflammation and immune regulation. By activating FPR2, 4-CMTB modulates neutrophil chemotaxis, cytokine release, and the resolution of inflammatory responses. It has been widely studied for its ability to promote pro-resolving pathways and attenuate excessive inflammation. Due to its specificity and potency, 4-CMTB is employed in research exploring innate immunity, inflammatory disease mechanisms, and the therapeutic potential of FPR2 modulation in conditions such as asthma, arthritis, and cardiovascular disorders.