4-Chloroquinoline-6-carbonitrile

• CAT Number: L026239
• CAS Number: 219763-83-4
• Molecular Formula: C10H5ClN2
• Molecular Weight: 188.61
• Purity: ≥95%
• IUPAC Name: 4-chloroquinoline-6-carbonitrile
• InChI: InChI=1S/C10H5ClN2/c11-9-3-4-13-10-2-1-7(6-12)5-8(9)10/h1-5H
• InChIKey: FLRGXIDFVYOCLP-UHFFFAOYSA-N
• SMILES: C1=CC2=NC=CC(=C2C=C1C#N)Cl

4-Chloroquinoline-6-carbonitrile（Cat No.:L026239）is a chlorinated quinoline derivative featuring a chlorine atom at the 4-position and a nitrile group at the 6-position of the quinoline ring system. This compound serves as a valuable intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of kinase inhibitors and antimalarial agents. The electron-withdrawing nitrile group and the reactive chlorine enable further functionalization through nucleophilic aromatic substitution or cross-coupling reactions. Its rigid, heteroaromatic structure supports strong binding interactions with biological targets, making it a useful scaffold in medicinal chemistry and heterocyclic compound design.