4-Chloro-3-methoxy-2-methylpyridine N-oxide

• CAT Number: R005033
• CAS Number: 122307-41-9
• Molecular Formula: C7H8ClNO2
• Molecular Weight: 173.60
• Purity: ≥95%
• Synonyms: 2-Methyl-3-methoxy-4-chloropyridine N-Oxide; 4-Chloro-2-methyl-3-methoxypyridine N-Oxide
• Storage: 4°C
• IUPAC Name: 4-chloro-3-methoxy-2-methyl-1-oxidopyridin-1-ium
• InChI: InChI=1S/C7H8ClNO2/c1-5-7(11-2)6(8)3-4-9(5)10/h3-4H,1-2H3
• InChIKey: TWXMQDRFBLSXFN-UHFFFAOYSA-N
• SMILES: CC1=[N+](C=CC(=C1OC)Cl)[O-]

4-Chloro-3-methoxy-2-methylpyridine N-oxide(CAT: R005033) is a functionalized pyridine N-oxide derivative featuring electron-donating (methoxy, methyl) and electron-withdrawing (chloro) groups strategically positioned on the aromatic ring. This compound is valuable in heterocyclic synthesis and serves as a versatile intermediate for designing bioactive molecules, particularly in pharmaceutical and agrochemical development. The N-oxide functionality enhances the reactivity of the pyridine ring in electrophilic substitution reactions and metal-catalyzed transformations. It is commonly used in medicinal chemistry for structure-activity relationship (SAR) studies and the synthesis of kinase inhibitors and CNS-active compounds. Its balanced polarity and stability make it suitable for diverse synthetic and research applications.