4-Chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine

• CAT Number: L043153
• CAS Number: 651744-48-8
• Molecular Formula: C16H25ClN2Si
• Molecular Weight: 308.92
• Purity: ≥95%
• IUPAC Name: (4-chloropyrrolo[2,3-b]pyridin-1-yl)-tri(propan-2-yl)silane
• InChI: InChI=1S/C16H25ClN2Si/c1-11(2)20(12(3)4,13(5)6)19-10-8-14-15(17)7-9-18-16(14)19/h7-13H,1-6H3
• InChIKey: HSMLARVFJADZQS-UHFFFAOYSA-N
• SMILES: CC(C)[Si](C(C)C)(C(C)C)N1C=CC2=C(C=CN=C21)Cl

4-Chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine（Cat No.:L043153）is a heteroaromatic compound featuring a pyrrolo[2,3-b]pyridine core with a chlorine atom at the 4-position and a triisopropylsilyl (TIPS) group protecting the nitrogen at the 1-position. The TIPS group enhances chemical stability and lipophilicity, often used to protect reactive N–H groups during multi-step organic synthesis. The 4-chloro substituent allows for further functionalization through cross-coupling reactions like Suzuki or Buchwald–Hartwig amination. This compound is a useful building block in medicinal chemistry, particularly in synthesizing kinase inhibitors and other bioactive heterocycles with pharmaceutical relevance.