4-Bromo-3-nitrobenzotrifluoride

• CAT Number: L048452
• CAS Number: 349-03-1
• Molecular Formula: C7H3BrF3NO2
• Molecular Weight: 270.21
• Purity: ≥95%
• IUPAC Name: 1-bromo-2-nitro-4-(trifluoromethyl)benzene
• InChI: InChI=1S/C7H3BrF3NO2/c8-5-2-1-4(7(9,10)11)3-6(5)12(13)14/h1-3H
• InChIKey: PESPBNYBZVIGRO-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C=C1C(F)(F)F)[N+](=O)[O-])Br

4-Bromo-3-nitrobenzotrifluoride(CAT: L048452) is a halogenated, electron-deficient aromatic compound featuring a trifluoromethyl group, a bromine atom at the 4-position, and a nitro group at the 3-position on a benzene ring. This compound is widely used as a synthetic intermediate in the preparation of agrochemicals, pharmaceuticals, and specialty materials. The bromine substituent facilitates palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck couplings, while the nitro and trifluoromethyl groups enhance reactivity and influence electronic properties for fine-tuning biological activity. Its stable structure and functional versatility make it an essential building block in fluorinated compound development and structure–activity relationship (SAR) studies.