4-Bromo-2-chloropyrimidine

• CAT Number: R034294
• CAS Number: 885702-34-1
• Molecular Formula: C4H2BrClN2
• Molecular Weight: 193.43
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 4-bromo-2-chloropyrimidine
• InChI: InChI=1S/C4H2BrClN2/c5-3-1-2-7-4(6)8-3/h1-2H
• InChIKey: FBEBVAQOMVWORE-UHFFFAOYSA-N
• SMILES: C1=CN=C(N=C1Br)Cl

4-Bromo-2-chloropyrimidine(CAT: R034294) is a halogenated heterocyclic compound featuring a pyrimidine ring substituted with bromine at the 4-position and chlorine at the 2-position. This dual halogenation provides versatile reactivity for sequential cross-coupling reactions, such as Suzuki, Stille, and Buchwald–Hartwig couplings, enabling the construction of diverse pyrimidine-based scaffolds. It serves as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and kinase inhibitors due to its compatibility with nucleophilic aromatic substitution and metal-catalyzed transformations.