4-Bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile

• CAT Number: M020349
• CAS Number: 122454-29-9
• Molecular Formula: C12H5BrClF3N2
• Molecular Weight: 349.54
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile
• InChI: InChI=1S/C12H5BrClF3N2/c13-9-8(5-18)10(19-11(9)12(15,16)17)6-1-3-7(14)4-2-6/h1-4,19H
• InChIKey: XNFIRYXKTXAHAC-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C2=C(C(=C(N2)C(F)(F)F)Br)C#N)Cl

4-Bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile（Cat No.:M020349）is a halogenated, trifluoromethylated pyrrole derivative with diverse functional groups offering broad synthetic utility. The molecule features a 4-chlorophenyl group at position 2, a trifluoromethyl group at position 5, a bromine atom at position 4, and a nitrile at position 3 of the pyrrole ring. This highly functionalized scaffold is valuable in medicinal chemistry, especially in designing kinase inhibitors, anti-inflammatory agents, or fluorinated bioactives. The trifluoromethyl and nitrile groups enhance lipophilicity and metabolic stability, while the aryl and halogen moieties allow for cross-coupling and further derivatization.