4-Azidobenzyl alcohol

• CAT Number: I042571
• CAS Number: 31499-54-4
• Molecular Formula: C7H7N3O
• Molecular Weight: 149.15
• Purity: ≥95%
• Synonyms: (4-azidophenyl)methanol
• InChI: InChI=1S/C7H7N3O/c8-10-9-7-3-1-6(5-11)2-4-7/h1-4,11H,5H2
• InChIKey: GEKVUCLUCOBNIE-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1CO)N=[N+]=[N-]

4-Azidobenzyl alcohol (Cat No.: I042571) is a benzyl alcohol derivative featuring an azide group at the para (4-) position of the aromatic ring. This compound is a valuable intermediate in organic synthesis and a key reagent in bioorthogonal click chemistry, especially in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. Its azido functionality enables selective conjugation to alkyne-bearing molecules, while the benzylic alcohol allows further functionalization. 4-Azidobenzyl alcohol is commonly used in the development of photoaffinity labels, bioconjugates, and functionalized materials for chemical biology research.

Reference

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.
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