4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one

• CAT Number: R003564
• CAS Number: 74853-07-9
• Molecular Formula: C19H21N5O2
• Molecular Weight: 351.41
• Purity: ≥95%
• Synonyms: 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one
• Storage: Store at RT
• IUPAC Name: 4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one
• InChI: InChI=1S/C19H21N5O2/c1-26-18-8-6-16(7-9-18)23-12-10-22(11-13-23)15-2-4-17(5-3-15)24-14-20-21-19(24)25/h2-9,14H,10-13H2,1H3,(H,21,25)
• InChIKey: SEHQVBVJJRRRSG-UHFFFAOYSA-N
• SMILES: COC1=CC=C(C=C1)N2CCN(CC2)C3=CC=C(C=C3)N4C=NNC4=O

4-{[4-(4-Methyloxyphenyl)piperazin-1-yl]phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one(CAT: R003564) is a complex heterocyclic compound incorporating a 1,2,4-triazolone core, a methoxyphenyl-substituted piperazine ring, and a phenyl linker. This structure is representative of pharmacophores commonly found in central nervous system (CNS)-active agents, particularly serotonin or dopamine receptor modulators. The triazolone moiety contributes to hydrogen bonding and potential bioactivity, while the piperazine ring provides enhanced receptor binding affinity and pharmacokinetic properties. This compound is useful in medicinal chemistry research for the development of anxiolytics, antidepressants, or antipsychotic agents, and may also serve as a key intermediate in synthesizing novel ligands targeting G-protein-coupled receptors or CNS enzymes.