4-​Isoxazoleboronic Acid Pinacol Ester

• CAT Number: R035690
• CAS Number: 928664-98-6
• Molecular Formula: C9H14BNO3
• Molecular Weight: 195.02
• Purity: ≥95%
• Synonyms: Isoxazol-4-ylboronic Acid Pinacol Ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-oxazole
• Storage: Store at -20C
• IUPAC Name: 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-oxazole
• InChI: InChI=1S/C9H14BNO3/c1-8(2)9(3,4)14-10(13-8)7-5-11-12-6-7/h5-6H,1-4H3
• InChIKey: LXCICYRNWIGDQA-UHFFFAOYSA-N
• SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CON=C2

4-Isoxazoleboronic acid pinacol ester(CAT: R035690) is a stable, boron-based reagent widely utilized in Suzuki–Miyaura cross-coupling reactions to form carbon–carbon bonds. Featuring a boronic ester group protected by pinacol and an isoxazole ring at the 4-position, it enables the efficient introduction of heterocyclic motifs into complex molecules. This compound is especially valuable in the synthesis of pharmaceuticals, agrochemicals, and materials where isoxazole-containing scaffolds are desired for their bioactivity and stability. Its good solubility, thermal stability, and compatibility with various reaction conditions make it an ideal building block for chemists designing heteroaryl biaryl structures in both research and industrial applications.