(3S,4R)-(-)-4-(4'-FLUOROPHENYL)3-HYDROXYMETHYL)-PIPERIDINE

• CAT Number: M015763
• CAS Number: 125224-43-3
• Molecular Formula: C12H16FNO
• Molecular Weight: 209.26
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: [(3S,4R)-4-(4-fluorophenyl)piperidin-3-yl]methanol
• InChI: InChI=1S/C12H16FNO/c13-11-3-1-9(2-4-11)12-5-6-14-7-10(12)8-15/h1-4,10,12,14-15H,5-8H2/t10-,12-/m0/s1
• InChIKey: IBOPBHBOBJYXTD-JQWIXIFHSA-N
• SMILES: C1CNCC(C1C2=CC=C(C=C2)F)CO

(3S,4R)-(–)-4-(4′-Fluorophenyl)-3-hydroxymethylpiperidine(CAT: M015763) is a chiral piperidine derivative featuring a 4-fluorophenyl group and a hydroxymethyl substituent, configured in the (3S,4R) stereoisomeric form. It is commonly used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of CNS-active agents, dopamine modulators, and antidepressants. The defined stereochemistry enables precise structure–activity relationship (SAR) studies and enhances target selectivity. This compound is valued for its role in synthesizing enantioselective APIs and for incorporation into complex heterocyclic scaffolds. Its combination of chirality and functional groups supports broad utility in drug discovery and medicinal chemistry.