(3R,​4R)​-N,​4-​Dimethyl-​1-​benzyl​-3-​piperidinamine

• CAT Number: R022804
• CAS Number: 477600-70-7
• Molecular Formula: C14H22N2
• Molecular Weight: 218.34
• Purity: ≥95%
• Synonyms: (3R,4R)-1-Benzyl-N-methyl-4-methylpiperidin-3-amine; (3R,​4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine
• Storage: Store at RT
• IUPAC Name: (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine
• InChI: InChI=1S/C14H22N2/c1-12-8-9-16(11-14(12)15-2)10-13-6-4-3-5-7-13/h3-7,12,14-15H,8-11H2,1-2H3/t12-,14+/m1/s1
• InChIKey: NVKDDQBZODSEIN-OCCSQVGLSA-N
• SMILES: CC1CCN(CC1NC)CC2=CC=CC=C2

(3R,4R)-N,4-Dimethyl-1-benzyl-3-piperidinamine(CAT: R022804) is a chiral, nitrogen-containing heterocycle featuring a substituted piperidine ring with defined stereochemistry. The (3R,4R) configuration imparts specific three-dimensional orientation, making it a valuable scaffold in medicinal chemistry for structure–activity relationship (SAR) exploration. The compound includes a benzyl group at the 1-position and methyl substituents on both the nitrogen and the 4-position, enhancing lipophilicity and modulating biological interactions. It is commonly used as a building block or intermediate in the synthesis of CNS-active agents, receptor ligands, and drug-like molecules. Its stereoselectivity and amine functionality support targeted design in pharmaceutical and bioactive compound development.