3,5-Difluorophenylboronic acid

• CAT Number: M094792
• CAS Number: 156545-07-2
• Molecular Formula: C6H5BF2O2
• Molecular Weight: 157.91
• Purity: ≥95%
• Storage: Desiccate at -20°C
• IUPAC Name: (3,5-difluorophenyl)boronic acid
• InChI: InChI=1S/C6H5BF2O2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,10-11H
• InChIKey: QWQBQRYFWNIDOC-UHFFFAOYSA-N
• SMILES: B(C1=CC(=CC(=C1)F)F)(O)O

3,5-Difluorophenylboronic acid (Cat No.: M094792) is an organoboron compound featuring a phenyl ring substituted with fluorine atoms at the 3 and 5 positions and a boronic acid group. This white to off-white crystalline solid is commonly used in Suzuki–Miyaura cross-coupling reactions to form biaryl and aryl–alkyl bonds. The difluoro substitution pattern enhances its electronic properties, making it valuable in the synthesis of pharmaceuticals, agrochemicals, and fluorinated materials. It serves as a versatile building block in modern organic and medicinal chemistry.