3,5-Dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine

• CAT Number: R041647
• CAS Number: 1149-23-1
• Molecular Formula: C13H19NO4
• Molecular Weight: 253.30
• Purity: ≥95%
• Synonyms: 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Diethyl Ester; 1,4-Dihydro-3,5-dicarboxylic Acid Diethyl Ester-2,6-dimethylpyridine; 2,6-Dimethyl-1,4-dihydropyridine-3,5-dicarboxylic Acid Diethyl Ester; 2,6-Dimethyl-3,5-di(carboethoxy)-1,4-dih
• Storage: Store at RT
• IUPAC Name: diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• InChI: InChI=1S/C13H19NO4/c1-5-17-12(15)10-7-11(13(16)18-6-2)9(4)14-8(10)3/h14H,5-7H2,1-4H3
• InChIKey: LJXTYJXBORAIHX-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C(NC(=C(C1)C(=O)OCC)C)C

3,5-Dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine(CAT: R041647) is a key structural motif belonging to the 1,4-dihydropyridine (DHP) class, widely recognized for its role in cardiovascular drug development, particularly as calcium channel blockers. Featuring ester groups at positions 3 and 5 and methyl substitutions at positions 2 and 6, this compound mimics the pharmacophore of clinically relevant agents like nifedipine. Its electron-rich, partially saturated pyridine ring allows for hydrogen donation and pi-interactions, making it a valuable scaffold in medicinal chemistry. Also used in mechanistic studies and structure-activity relationship (SAR) modeling.