3,5-Di-O-(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl Chloride

• CAT Number: R048827
• CAS Number: 21740-23-8
• Molecular Formula: C₁₉H₁₅Cl₃O₅
• Molecular Weight: 429.68
• Purity: ≥95%
• Synonyms: 2-Deoxy-α-D-erythro-pentofuranosyl Chloride 3,5-Bis(4-chlorobenzoate); 1-Chloro-2-deoxy-3,5-O-bis(p-chlorobenzoyl)-α-D-erythro-pentofuranose; 3,5-Bis(4-chlorobenzoyl)-2-deoxy-.alpha.-D-ribofuranosyl Chloride; NSC 140594
• Storage: -20°C
• IUPAC Name: [5-chloro-3-(4-chlorobenzoyl)oxyoxolan-2-yl]methyl 4-chlorobenzoate
• InChI: InChI=1S/C19H15Cl3O5/c20-13-5-1-11(2-6-13)18(23)25-10-16-15(9-17(22)26-16)27-19(24)12-3-7-14(21)8-4-12/h1-8,15-17H,9-10H2
• InChIKey: QEHCZULNFYDPPL-UHFFFAOYSA-N
• SMILES: C1C(C(OC1Cl)COC(=O)C2=CC=C(C=C2)Cl)OC(=O)C3=CC=C(C=C3)Cl

3,5-Di-O-(p-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl chloride(CAT: R048827) is a protected sugar derivative commonly used as a key intermediate in nucleoside synthesis. It features a 2-deoxyribose backbone with p-chlorobenzoyl protecting groups at the 3- and 5-hydroxyl positions and a chloride substituent at the anomeric carbon (C1), which allows for efficient glycosylation reactions. This compound is crucial in the chemical synthesis of modified nucleosides, especially for antiviral and anticancer research. The p-chlorobenzoyl groups enhance stability and selectivity during coupling reactions.