3,5-Bis(trifluoromethyl)aniline

• CAT Number: L047627
• CAS Number: 328-74-5
• Molecular Formula: C8H5F6N
• Molecular Weight: 229.12
• Purity: ≥95%
• IUPAC Name: 3,5-bis(trifluoromethyl)aniline
• InChI: InChI=1S/C8H5F6N/c9-7(10,11)4-1-5(8(12,13)14)3-6(15)2-4/h1-3H,15H2
• InChIKey: CDIDGWDGQGVCIB-UHFFFAOYSA-N
• SMILES: C1=C(C=C(C=C1C(F)(F)F)N)C(F)(F)F

3,5-Bis(trifluoromethyl)aniline(CAT: L047627) is a fluorinated aromatic amine featuring two trifluoromethyl groups at the 3- and 5-positions of the benzene ring and an amino group at the para position. This electron-deficient aniline derivative is widely used in pharmaceutical, agrochemical, and material science research as a building block for synthesizing fluorinated bioactive molecules. The CF₃ groups enhance lipophilicity, metabolic stability, and binding affinity, while the amino group enables coupling reactions such as urea, amide, and heterocycle formation. Its unique electronic properties make it particularly valuable in designing enzyme inhibitors, fluorinated dyes, and advanced organic materials with tailored electronic or biological profiles.