3,4-Dihydroxyphenylacetic Acid

• CAT Number: R057933
• CAS Number: 102-32-9
• Molecular Formula: C8H8O4
• Molecular Weight: 168.15
• Purity: ≥95%
• Synonyms: 3,4-Dihydroxybenzeneacetic Acid; (3,4-Dihydroxyphenyl)acetic Acid; Ba 2773; DOPAC; Dihydroxyphenylacetic Acid; Dopacetic Acid; Homoprotocatechuic Acid
• Storage: Store at -20°C
• IUPAC Name: 2-(3,4-dihydroxyphenyl)acetic acid
• InChI: InChI=1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
• InChIKey: CFFZDZCDUFSOFZ-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C=C1CC(=O)O)O)O

3,4-Dihydroxyphenylacetic Acid (CAT: R057933) is a major metabolite of the neurotransmitter dopamine, formed via monoamine oxidase-mediated deamination. It is extensively used in neurochemical research to monitor dopamine metabolism, turnover, and neuronal activity, particularly in studies of Parkinson’s disease, schizophrenia, and drug addiction. DOPAC levels in biological fluids serve as important biomarkers for dopaminergic function. It also plays a role in oxidative stress research due to its catechol structure, which can undergo redox cycling.