3,4-Dihydro-1,5-naphthyridin-2(1H)-one

• CAT Number: L022829
• CAS Number: 943537-93-7
• Molecular Formula: C8H8N2O
• Molecular Weight: 148.16
• Purity: ≥95%
• IUPAC Name: 3,4-dihydro-1H-1,5-naphthyridin-2-one
• InChI: InChI=1S/C8H8N2O/c11-8-4-3-6-7(10-8)2-1-5-9-6/h1-2,5H,3-4H2,(H,10,11)
• InChIKey: LMORUQRSHZOMKO-UHFFFAOYSA-N
• SMILES: C1CC(=O)NC2=C1N=CC=C2

3,4-Dihydro-1,5-naphthyridin-2(1H)-one（Cat No.:L022829）is a bicyclic heterocyclic compound featuring a partially saturated 1,5-naphthyridine core with a ketone group at the 2-position. Its structure combines a pyridine ring fused with a dihydropyridine ring, offering both aromatic and reduced characteristics. This scaffold is of significant interest in medicinal chemistry due to its resemblance to bioactive pharmacophores found in antibacterial, antiviral, and CNS-targeting agents. The ketone group serves as a reactive site for derivatization, while the nitrogen atoms enhance hydrogen bonding potential, making it a valuable intermediate for drug design and heterocyclic compound synthesis.