3,4-Dibromo-Mal-PEG8-Boc

• CAT Number: I015701
• CAS Number: 2055198-02-0
• Molecular Formula: C27H45Br2NO12
• Molecular Weight: 735.45
• Purity: ≥95%
• Synonyms: tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-[2-(3,4-dibromo-2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C27H45Br2NO12/c1-27(2,3)42-22(31)4-6-34-8-10-36-12-14-38-16-18-40-20-21-41-19-17-39-15-13-37-11-9-35-7-5-30-25(32)23(28)24(29)26(30)33/h4-21H2,1-3H3
• InChIKey: NRCHSTUDEZBNCB-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)C(=C(C1=O)Br)Br

3,4-Dibromo-Mal-PEG8-Boc（Cat No.:I015701）is a heterobifunctional polyethylene glycol derivative designed as a versatile linker for chemical biology and bioconjugation. It incorporates a maleimide (Mal) moiety for selective thiol-reactivity, two bromine atoms for further substitution or crosslinking, and a Boc-protected amine for orthogonal deprotection and conjugation. The PEG8 spacer ensures hydrophilicity, extended reach, and minimized steric hindrance, enhancing solubility and flexibility in aqueous and organic systems. This reagent is widely employed in protein–drug conjugates, advanced biomaterials, and synthetic chemistry applications where multifunctional linkers are required.