3,4-Dibromo-Mal-PEG2-amine TFA

• CAT Number: I045292
• CAS Number: 2296708-07-9
• Molecular Formula: C12H15Br2F3N2O6
• Molecular Weight: 500.06
• Purity: ≥95%
• Synonyms: 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-3,4-dibromopyrrole-2,5-dione;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C10H14Br2N2O4.C2HF3O2/c11-7-8(12)10(16)14(9(7)15)2-4-18-6-5-17-3-1-13;3-2(4,5)1(6)7/h1-6,13H2;(H,6,7)
• InChIKey: MGVSSFASAOVDDG-UHFFFAOYSA-N
• SMILES: C(COCCOCCN1C(=O)C(=C(C1=O)Br)Br)N.C(=O)(C(F)(F)F)O

3,4-Dibromo-Mal-PEG2-amine TFA（Cat No.:I045292）is a heterobifunctional PEG linker containing a maleimide group, a dibromo-substituted aromatic moiety, and a terminal amine, supplied as a trifluoroacetate salt for enhanced stability. The maleimide group enables selective conjugation to thiol-containing biomolecules, while the amine allows coupling to activated carboxyl groups or other reactive species. The PEG2 spacer improves water solubility, reduces steric hindrance, and increases molecular flexibility. This reagent is widely used in bioconjugation, drug delivery system design, and the preparation of antibody–drug conjugates (ADCs), enabling precise and stable attachment of functional payloads to biological targets.