3,3-Dimethyl-6-nitroindolin-2-one

• CAT Number: L034704
• CAS Number: 100510-64-3
• Molecular Formula: C10H10N2O3
• Molecular Weight: 206.2
• Purity: ≥95%
• IUPAC Name: 3,3-dimethyl-6-nitro-1H-indol-2-one
• InChI: InChI=1S/C10H10N2O3/c1-10(2)7-4-3-6(12(14)15)5-8(7)11-9(10)13/h3-5H,1-2H3,(H,11,13)
• InChIKey: JTVMMOAEEVKAGQ-UHFFFAOYSA-N
• SMILES: CC1(C2=C(C=C(C=C2)[N+](=O)[O-])NC1=O)C

3,3-Dimethyl-6-nitroindolin-2-one(CAT: L034704) is a nitro-substituted indolinone derivative featuring two methyl groups at the 3-position and a nitro group at the 6-position of the aromatic ring. This compound is a valuable intermediate in medicinal chemistry and heterocyclic synthesis, offering a reactive framework for further functionalization through reduction, substitution, or cyclization. The indolinone core is a privileged structure found in many bioactive molecules, including kinase inhibitors and anticancer agents. The electron-withdrawing nitro group influences reactivity and electronic properties, enabling structure–activity relationship (SAR) exploration. Its rigid bicyclic scaffold makes it useful in the development of pharmaceuticals, agrochemicals, and fluorescent probes.