3,3’-Diiodo-L-thyronine

• CAT Number: R000847
• CAS Number: 4604-41-5
• Molecular Formula: C15H13I2NO4
• Molecular Weight: 525.08
• Purity: ≥95%
• Synonyms: 3,3’-T2; O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine; 3-[4-(4-Hydroxy-3-iodophenoxy)-3-iodophenyl]-L-alanine
• Target: Immunology/Inflammation
• Storage: -20°C
• IUPAC Name: (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid
• InChI: InChI=1S/C15H13I2NO4/c16-10-7-9(2-3-13(10)19)22-14-4-1-8(5-11(14)17)6-12(18)15(20)21/h1-5,7,12,19H,6,18H2,(H,20,21)/t12-/m0/s1
• InChIKey: CPCJBZABTUOGNM-LBPRGKRZSA-N
• SMILES: C1=CC(=C(C=C1C[C@@H](C(=O)O)N)I)OC2=CC(=C(C=C2)O)I

3,3’-Diiodo-L-thyronine (Cat No.:R000847) is a naturally occurring iodinated derivative of the thyroid hormone family, structurally related to triiodothyronine (T3) and thyroxine (T4). It contains two iodine atoms on the inner rings of the thyronine backbone and plays a role in regulating metabolic activity. T2 is studied for its rapid, non-genomic effects on mitochondrial respiration, energy expenditure, and lipid metabolism without triggering typical thyroid hormone receptor-mediated transcription. It is typically used in endocrinology and metabolic research and is of interest as a potential therapeutic agent in obesity and metabolic disorders.