3-(Trifluoromethyl)benzoic acid

• CAT Number: M209601
• CAS Number: 454-92-2
• Molecular Formula: C8H5F3O2
• Molecular Weight: 190.12
• Purity: ≥95%
• IUPAC Name: 3-(trifluoromethyl)benzoic acid
• InChI: InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)
• InChIKey: FQXQBFUUVCDIRK-UHFFFAOYSA-N
• SMILES: C1=CC(=CC(=C1)C(F)(F)F)C(=O)O

3-(Trifluoromethyl)benzoic acid(CAT: M209601) is a fluorinated aromatic carboxylic acid characterized by a trifluoromethyl group at the meta-position relative to the carboxyl group. The CF₃ substituent imparts strong electron-withdrawing properties and metabolic stability, making this compound highly valuable in medicinal chemistry, agrochemical synthesis, and materials science. It serves as a versatile building block for constructing fluorinated bioactive molecules, enhancing lipophilicity, membrane permeability, and binding affinity. The carboxylic acid functionality enables easy derivatization into esters, amides, or anhydrides. This reagent is ideal for SAR studies, fluorinated compound libraries, and fine chemical production where fluorine effects are desired.